Colorectal Carcinoma: Prognostic Significance of Gastrin

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Prognostic significance of CXCL12 expression in patients with colorectal carcinoma.

The present study investigated the protein expression level of CXCL12 in colorectal cancer and aimed to elucidate its association with prognosis. CXCL12 positivity in 50% or more of tumor cells was defined as high expression and that in less than 50% of the tumor cells as low expression. CXCL12+ tumor budding at the invasive front was divided into 2 grades: high with 10 or more budding foci per...

متن کامل

COLORECTAL CANCER The prognostic significance of K-ras, p53, and APC mutations in colorectal carcinoma

Background: Accumulation of molecular alterations, including mutations in Kirsten-ras (K-ras), p53, and adenomatous polyposis coli (APC), contribute to colorectal carcinogenesis. Our group has previously characterised a panel of sporadic colorectal adenocarcinomas for mutations in these three genes and has shown that p53 and K-ras mutations rarely occur in the same colorectal tumour. This sugge...

متن کامل

Prognostic significance of E-Cadherin and CD44 expression in tumor tissue of colorectal carcinoma

Background Colorectal cancer (CRC) is a major cause of cancer-related mortality worldwide. Currently, tumor-node-metastasis staging system still remains the gold standard for prognosis of CRC patients, but it is no longer sufficient. Among the most important molecules involved in colorectal tumor growth, cell proliferation and progression are adhesive molecules such as CD44 and E-cadherin (EC)....

متن کامل

Analysis of prognostic factors in colorectal carcinoma.

UNLABELLED Colorectal cancer is one of the most common malignancies in development countries. The purpose of this study was to analyze the epidemiologic profiles of the disease, to examine the results of survival at five years after diagnosis and how it was influenced by pathological aspects. MATERIAL AND METHODS In collaboration with Oncologic Clinic all colorectal cancer diagnosed from Janu...

متن کامل

Prognostic significance of p53-expression in colorectal carcinoma as measured by a luminometric immunoassay

BACKGROUND Mutations of the TP53 gene induce the production of abnormal p53-protein with a prolonged half-life allowing its detection by monoclonal antibodies. In the following study we examined if elevated levels of p53 correlate with worse prognosis in colorectal cancer. METHODS We have quantified the protein, using an immunoluminometric assay, in 144 cytosols of primary sporadic colorectal...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: JNCI Journal of the National Cancer Institute

سال: 1995

ISSN: 0027-8874,1460-2105

DOI: 10.1093/jnci/87.14.1086